Blog

New paper on cell type evolution in placozoans and the early origin of the neuron expression programme

We have recently published a new paper on cell type evolution in four placozoan species using single-cell transcriptomics. We explore their cell type diversity and study their evolution within the Placozoa phylum and beyond.

Ill fares the land

Ill fares the land, to hastening ills a prey, Oliver Goldsmith.

New paper on chromatin evolution in eukaryotes

We have recently published a new paper on the evolution of chromatin in eukaryotes:

Recoded protein mixture models for IQ-TREE

I have set up a Github repository with NEXUS files of mixture models for some common amino-acid recoding schemes (Dayhoff6, Dayhoff9, SR4, SR6, KGB6). They can be used in IQ-TREE with the -mdef flag, which allows you to use non-default models.

La font del mirall

La font del mirall, Joan Brossa.

Dos micos, de Brueghel

Dwie małpy Bruegla (Dos micos de Brueghel), Wisława Szymborska.

Predicting the effects of alternative splicing events with VEP

This post is a stub. How can we predict the effects of alternative splicing (AS) events with the Ensembl Variant Effect Predictor (VEP)? In our recent paper in eLife, we did so by encoding them as if they were indels.

«Uns per por i altres per pena»

Cançoneta Juganera 2 (Ovidi Montllor)

Tyger, tyger — Tigre, tigre

The Tyger (William Blake, 1794)

A refusal to mourn the death, by fire, of a child in London

A Refusal To Mourn The Death, By Fire, Of A Child In London (Dylan Thomas, 1945)

Indesinenter — incessantment — ceaselessly

Indesinenter (Salvador Espriu).

«Do not go gentle into that good night»

Do not go gentle into that good night (Dylan Thomas, 1947)

«The Disciple», modern

When Narcissus died the pool of his pleasure changed from a cup of sweet waters into a cup of salt tears, and the Oreads came weeping through the woodland that they might sing to the pool and give it comfort.

Paraphelidium transcriptome: some code

This is a quick post to highlight the publication of Global transcriptome analysis of the aphelid Paraphelidium tribonemae supports the phagotrophic origin of fungi by Guifré Torruella, Purificación López-García (Université Paris-Sud) et al., in Communications Biology.

Evolution of alternative splicing in eukaryotes

After a few years of work with Iñaki Ruiz-Trillo (IBE and ICREA) and Manuel Irimia (CRG), the last paper from my PhD thesis has just been published in Genome Biology — you can read it here (open access, of course).

«Remember first to possess his books»

Act 3, Scene 2, 71-79

«I tan mateix»

Aquesta remor que se sent (Miquel Martí i Pol, 1971)